Zhao P, El Fadel O, Le A, Mangleburg CG, Dhindsa J, Wu T, Zhao J, Huang M, Amoh B, Marella AS, Li Y, Seyfried NT, Levey AI, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer’s disease. Mol Psychiatry. 2026 Feb 14. doi: 10.1038/s41380-026-03479-6. […]
Pugh DA, Cary GA, Greathouse KM, Nassour-Caswell LC, Hobby EL, Seyfried NT, Herskowitz JH. NRN1 as a therapeutic target for Alzheimer’s disease. Alzheimers Dement. 2026 Feb;22(2):e71149. doi: 10.1002/alz.71149. PMID: 41645874; PMCID: PMC12877949.
Libby JB, Deters KD, Ertekin-Taner N, Carrasquillo MM, Allen M, De Jager P, Menon V, Zhang B, Haroutunian V, Levey AI, Seyfried NT, Kaddurah-Daouk R, Finkbeiner S, Wang D, Greenwood AK, Vander Linden A, Heath L, Poehlman WL, Dumitrescu L, Petyuk VA, Bennett DA, Schneider JA, Barnes LL, Hohman TJ. Multi-omic expression of the VEGF […]
Mohs RC, Beauregard DW, Hughes L, Cordell CB, Levey AI, Rathore S, Seyfried NT, Johnson ECB, Nicodemus-Johnson J, Christensen J, Wolz R, Dwyer J. Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer’s disease but without amyloid deposits on positron emission tomography: Results from Bio-Hermes Study participants. Alzheimers Dement. 2026 Jan;22(1):e71085. […]
Zhou L, Jeong IH, Li H, Rios N, Zhang J, Wang X, Liu S, Xie Y, Wei W, Jeong GH, Duong D, Seyfried NT, Xue B, Shi H, Mabb AM, Wang Y, Kiyokawa H, Yin J. Engineering an orthogonal ubiquitin transfer cascade with Ring E3 RNF38 by phage display to reveal its regulation of nuclear […]
Sesay F, Zhang H, Kapoor-Vazirani P, Jung AT, Essien ME, Bastien AJ, Luong NC, Liu X, Head PE, Duong DM, Yang X, Buchwald ZS, Deng X, Seyfried NT, Yu DS. MRE11 deacetylation by SIRT2 promotes DNA binding to facilitate DNA end resection and ATM-dependent signaling. J Clin Invest. 2026 Jan 8:e186711. doi: 10.1172/JCI186711. Epub ahead […]