Butler CA, Gee MS, O’Gara K, Milinkeviciute G, Da Cunha C, Kawauchi S, Lu YH, Kwang N, Tsourmas KI, Prekopa C, Shi Z, Liang HY, Collins SD, Pashkutz ZA, Sanchez JA, Shi KX, Walker AD, Wang S, Wong MLA, Genaro K, Neumann J, Gomez-Arboledas A, Duong DM, Seyfried NT, Tenner AJ, LaFerla FM, Mortazavi A, […]
Liu Q, Parrish RL, Tang S, Tasaki S, Bennett DA, Seyfried NT, De Jager PL, Menon V, Buchman AS, Yang J. Cell-type-aware transcriptome-wide association studies identify 91 independent risk genes for Alzheimer’s disease dementia. Commun Biol. 2026 Apr 22. doi: 10.1038/s42003-026-10030-4. Epub ahead of print. PMID: 42020711.
Lange-Maia BS, Vialle RA, Wang T, Zammit AR, Farfel J, Seyfried NT, Bennett DA, Buchman AS. Proteome-wide association study of cortical proteins that may provide resilience for late-life disability. J Gerontol A Biol Sci Med Sci. 2026 Apr 17:glag101. doi: 10.1093/gerona/glag101. Epub ahead of print. PMID: 41999218.
Di Caro V, Cho E, Thiel J, Lizama BN, Koel-Simmelink MJA, Pandey K, Duong D, Seyfried NT, Grundman M, Teunissen CE, Zetterberg H, Blennow K, Caggiano AO, Hamby ME. Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer’s disease. […]
Hobby EL, Weber AJ, Liu E, Hurst C, Greathouse KM, Gaiteri C, Seyfried NT, Herskowitz JH. A Multi-Network Approach Identifies Proteins Related to Dendritic Spines in Alzheimer’s Disease. eNeuro. 2026 Apr 1:ENEURO.0468-25.2026. doi: 10.1523/ENEURO.0468-25.2026. Epub ahead of print. PMID: 41922169.
Ramelow CC, Dammer EB, Xiao H, Cheng L, Kumar P, Espinosa-Garcia C, Sampson MM, Kour D, Nelson RS, Malepati S, Kumari R, Jang WE, Guo Q, Bagchi P, Duong DM, Seyfried NT, Sloan SA, Rangaraju S. Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling. Nat Commun. 2026 Mar 31. […]
Shrestha HK, Sun H, Yarbro JM, Lee D, Liu D, Wang E, McReynolds M, Zhang N, Xie B, Yang S, Yu K, Poudel S, Li Y, Yuan ZF, Kong D, Wang M, Wang Z, Niu M, Wang H, Zaman M, Wang J, Vanderwall DR, Sun Y, Wu Z, Chen PC, Bai B, High AA, Faura […]
Trautwig AN, Shantaraman A, Chung M, Dammer EB, Ping L, Duong DM, Watson CM, Petrucelli L, Ward ME, Glass JD, Nelson PT, Levey AI, McEachin ZT, Seyfried NT. Subtyping based on hippocampal cryptic exon burden reveals proteome-wide changes associated with TDP-43 and Alzheimer’s disease pathology. Cell Rep. 2026 Mar 18;45(4):117142. doi: 10.1016/j.celrep.2026.117142. Epub ahead of […]
Lessard CB, Rubio Rubio D, Tolton S, Criado-Marrero M, Ravi S, Garza TN, Koren J 3rd, Philips J, Bagchi P, McFarland K, Chhangani D, Golde T, Giasson BI, Lewis J, Chakrabarty P, LaVoie MJ, Borchelt D, Seyfried NT, Prokop S, Rincon-Limas DE, Abisambra JF. Progressive Supranuclear Palsy PERK haplotype B selectively translates DLX1 promoting tau […]
Zhao P, El Fadel O, Le A, Mangleburg CG, Dhindsa J, Wu T, Zhao J, Huang M, Amoh B, Marella AS, Li Y, Seyfried NT, Levey AI, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer’s disease. Mol Psychiatry. 2026 Feb 14. doi: 10.1038/s41380-026-03479-6. […]