Olah VJ, Goettemoeller AM, Rayaprolu S, Dammer EB, Seyfried NT, Rangaraju S, Dimidschstein J, Rowan MJM. Biophysical K(v)3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer’s. Elife. 2022;11. Epub 2022/06/22. doi: 10.7554/eLife.75316. PubMed PMID: 35727131; PMCID: PMC9278953.
Johnson MA, Nuckols TA, Merino P, Bagchi P, Nandy S, Root J, Taylor G, Seyfried NT, Kukar T. Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome. J Biol Chem. 2022;298(8):102135. Epub 2022/06/17. doi: 10.1016/j.jbc.2022.102135. PubMed PMID: 35709984; PMCID: PMC9372748.
Eninger T, Müller SA, Bacioglu M, Schweighauser M, Lambert M, Maia LF, Neher JJ, Hornfeck SM, Obermüller U, Kleinberger G, Haass C, Kahle PJ, Staufenbiel M, Ping L, Duong DM, Levey AI, Seyfried NT, Lichtenthaler SF, Jucker M, Kaeser SA. Signatures of glial activity can be detected in the CSF proteome. Proc Natl Acad Sci […]
Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, Hajjar I, Fagan AM, Galasko D, Edland SD, Hanfelt J, Lah JJ, Weinshenker D. A phase II study repurposing atomoxetine for neuroprotection in mild […]
Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, Wood LB, Seyfried NT, Rangaraju S. Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nat Commun. 2022;13(1):2927. […]
Trumpff C, Owusu-Ansah E, Klein HU, Lee AJ, Petyuk V, Wingo TS, Wingo AP, Thambisetty M, Ferrucci L, Seyfried NT, Bennett DA, De Jager PL, Picard M. Mitochondrial respiratory chain protein co-regulation in the human brain. Heliyon. 2022;8(5):e09353. Epub 2022/05/24. doi: 10.1016/j.heliyon.2022.e09353. PubMed PMID: 35600441; PMCID: PMC9118667.
Wingo TS, Gerasimov ES, Liu Y, Duong DM, Vattathil SM, Lori A, Gockley J, Breen MS, Maihofer AX, Nievergelt CM, Koenen KC, Levey DF, Gelernter J, Stein MB, Ressler KJ, Bennett DA, Levey AI, Seyfried NT, Wingo AP. Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder. Mol Psychiatry. […]
Zhang H, Dammer EB, Duong DM, Danelia D, Seyfried NT, Yu DS. Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Sci Rep. 2022;12(1):3822. Epub 2022/03/11. doi: 10.1038/s41598-022-06793-5. PubMed PMID: 35264593; PMCID: PMC8907344.
Yu L, Boyle PA, Wingo AP, Yang J, Wang T, Buchman AS, Wingo TS, Seyfried NT, Levey AI, De Jager PL, Schneider JA, Bennett DA. Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology. 2022;98(10):e1031-e9. Epub 2021/12/24. doi: 10.1212/wnl.0000000000013252. PubMed PMID: 34937778; PMCID: PMC8967389.
Wu CI, Vinton EA, Pearse RV, 2nd, Heo K, Aylward AJ, Hsieh YC, Bi Y, Adeleye S, Fancher S, Duong DM, Seyfried NT, Schwarz TL, Young-Pearse TL. APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons. Mol Psychiatry. 2022;27(4):1970-89. Epub 2022/02/24. doi: 10.1038/s41380-022-01454-5. PubMed PMID: 35194165; […]
