Dammer EB, Ping L, Duong DM, Modeste ES, Seyfried NT, Lah JJ, Levey AI, Johnson ECB. Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimers Res Ther. 2022;14(1):174. Epub 2022/11/18. doi: 10.1186/s13195-022-01113-5. PubMed PMID: 36384809; PMCID: PMC9670630.
Sohn AL, Ping L, Glass JD, Seyfried NT, Hector EC, Muddiman DC. Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI). Metabolites. 2022;12(11). Epub 2022/11/11. doi: 10.3390/metabo12111096. PubMed PMID: 36355179; PMCID: PMC9696666.
Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok AHYS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, Alcolea D, Lleó A, Levey AI, Lemstra AW, Pijnenburg YAL, Visser PJ, Tijms BM, van der Flier WM, Teunissen CE. CSF proteome […]
Kapoor-Vazirani P, Rath SK, Liu X, Shu Z, Bowen NE, Chen Y, Haji-Seyed-Javadi R, Daddacha W, Minten EV, Danelia D, Farchi D, Duong DM, Seyfried NT, Deng X, Ortlund EA, Kim B, Yu DS. SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks. Nat Commun. 2022;13(1):6707. Epub 2022/11/08. doi: […]
Suttapitugsakul S, Stavenhagen K, Donskaya S, Bennett DA, Mealer RG, Seyfried NT, Cummings RD. Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer’s Disease Brain. Mol Cell Proteomics. 2022;21(12):100433. Epub 2022/10/30. doi: 10.1016/j.mcpro.2022.100433. PubMed PMID: 36309312; PMCID: PMC9706167.
Hsieh YC, Negri J, He A, Pearse RV, 2nd, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL. Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity. Mol Neurodegener. 2022;17(1):61. Epub 2022/09/22. doi: 10.1186/s13024-022-00558-4. PubMed PMID: 36131294; PMCID: PMC9494921.
Yu L, Hsieh YC, Pearse RV, Wang Y, Petyuk VA, Schneider JA, Buchman AS, Seyfried NT, De Jager PL, Young-Pearse TL, Bennett DA. Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study. Neurology. 2022;99(20):e2264-e74. Epub 2022/08/11. doi: 10.1212/wnl.0000000000201120. PubMed PMID: 35948448; PMCID: PMC9694839.
Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nat Commun. 2022;13(1):4314. Epub 2022/07/27. doi: 10.1038/s41467-022-31873-5. PubMed PMID: 35882878; PMCID: PMC9325708.
Batra R, Arnold M, Wörheide MA, Allen M, Wang X, Blach C, Levey AI, Seyfried NT, Ertekin-Taner N, Bennett DA, Kastenmüller G, Kaddurah-Daouk RF, Krumsiek J. The landscape of metabolic brain alterations in Alzheimer’s disease. Alzheimers Dement. 2022. Epub 2022/07/14. doi: 10.1002/alz.12714. PubMed PMID: 35829654; PMCID: PMC9837312.
Nelson RS, Dammer EB, Santiago JV, Seyfried NT, Rangaraju S. Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms. Front Neurosci. 2022;16:902146. Epub 2022/07/06. doi: 10.3389/fnins.2022.902146. PubMed PMID: 35784845; PMCID: PMC9243337.